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PRADAXA is a prescription blood-thinning medicine used to reduce the risk of stroke and blood clots in people with atrial fibrillation (AFib) not caused by a heart valve problem.
PRADAXA represents progress in helping to reduce the risk of stroke due to atrial fibrillation (AFib) not caused by a heart valve problem.
Review the chart below to compare PRADAXA and warfarin (Coumadin® or Jantoven®). And find out why your doctor may choose PRADAXA. Remember, only your doctor can decide which treatment may be right for you.
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Medication type: PRADAXA and warfarin work differently to help reduce the risk of stroke due to AFib not caused by a heart valve problem. |
PRADAXA is a direct thrombin inhibitor that helps to stop clots from forming by working directly on thrombin. |
Warfarin is a vitamin K antagonist that helps to stop clots from forming by interfering with vitamin K—a vitamin your body needs to form clots. |
Stroke risk reduction: |
In a clinical trial of more than 18,000 people, PRADAXA 150 mg capsules reduced the risk of stroke 35% more than warfarin. Risk reduction was greatest when compared to patients on warfarin whose blood tests showed lower levels of control. |
Warfarin has been extensively studied and prescribed by doctors to help reduce the risk of stroke in people with AFib since 1954. |
How you take the medication: |
PRADAXA is taken by mouth 2 times each day—with or without food. |
Warfarin is taken by mouth once every day—with or without food. |
Dosing options: |
PRADAXA comes in 75 mg and 150 mg strengths. Your doctor will decide which dose is right for you. |
Warfarin comes in 1 mg, 2 mg, 2-1/2 mg, 3 mg, 4 mg, 5 mg, 6 mg, 7-1/2 mg, and 10 mg strengths. Your doctor will decide which dose is right for you. He or she will adjust your dose based on the results of regular blood tests. Based on these tests, your doctor will determine your dose and adjust it, if necessary. |
Monitoring: |
No need for regular blood tests. PRADAXA has been clinically proven to help reduce the risk of stroke in people with AFib not caused by a heart valve problem. And, unlike warfarin, there is no need for regular blood tests to see if your blood-thinning level is in the right range. Learn more  |
Requires regular blood test. Warfarin has also been proven to be an effective blood thinner. When you take warfarin, you need to have a regular blood test to measure International Normalized Ratio (INR) to determine the time it takes for your blood to clot. |
Dietary restrictions: |
No dietary restrictions PRADAXA requires no changes to your diet. |
Dietary restrictions required When you take warfarin, you need to avoid foods high in vitamin K, such as large amounts of leafy green vegetables and some vegetable oils. This is because Vitamin K can affect the way warfarin works in your body. You also need to avoid alcohol, cranberry juice, and products containing cranberries. |
If you have AFib not caused by a heart valve problem, even if you take warfarin, ask your doctor about PRADAXA 
Create a personalized doctor discussion guide. And help make sure you get the answers you need about AFib not caused by a heart valve problem, stroke, and treating with PRADAXA.
You could be eligible to save on your prescription or get one FREE 30-day supply of PRADAXA*.
* Pay no more than $30 if you have commercial insurance, with a maximum benefit of $100 on your monthly prescription over a 12-month period. If you are covered by a government-funded insurance, or are cash paying, or live in the state of Massachusetts, you are eligible for one FREE 30-day supply of PRADAXA.
WHAT IS PRADAXA?
PRADAXA is a prescription blood-thinning medicine used to reduce the risk of stroke and blood clots in people with atrial fibrillation not caused by a heart valve problem. With atrial fibrillation, part of the heart does not beat the way it should. This can cause blood clots to form, increasing your risk of a stroke. PRADAXA lowers the chance of blood clots forming in your body.
IMPORTANT SAFETY INFORMATION ABOUT PRADAXA
PRADAXA can cause bleeding which can be serious and sometimes lead to death. Don’t take PRADAXA if you currently have abnormal bleeding or if you have ever had an allergic reaction to it.
Your risk of bleeding with PRADAXA may be higher if you:
- • are 75 years old or older
- • have kidney problems
- • have stomach or intestine bleeding that is recent or keeps coming back or you have a stomach ulcer
- • take other medicines that increase your risk of bleeding, like aspirin products, non-steroidal anti-inflammatory drugs (NSAIDs) and blood thinners
- • have kidney problems and take dronedarone (Multaq®) or ketoconazole tablets (Nizoral®)
Call your doctor or seek immediate medical care if you have any of the following signs or symptoms of bleeding:
- • any unexpected, severe, or uncontrollable bleeding; or bleeding that lasts a long time
- • unusual or unexpected bruising
- • coughing up or vomiting blood; or vomit that looks like coffee grounds
- • pink or brown urine; red or black stools (looks like tar)
- • unexpected pain, swelling, or joint pain
- • headaches and feeling dizzy or weak
It is important to tell your doctor about all medicines, vitamins and supplements you take. Some of your other medicines may affect the way PRADAXA works.
Take PRADAXA exactly as prescribed by your doctor. Don’t stop taking PRADAXA without talking to your doctor as your risk of stroke may increase.
Tell your doctor if you are planning to have any surgery, or medical or dental procedure, because you may have to stop taking PRADAXA for a short time.
PRADAXA can cause indigestion, stomach upset or burning, and stomach pain.
Click here for full Prescribing Information including Medication Guide
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call
1-800-FDA-1088.
The health information contained in this Website is provided for educational purposes only and is not intended to replace discussions with a healthcare professional. All decisions regarding patient care must be made with a healthcare professional, considering the unique characteristics of the patient.
IMPORTANT SAFETY INFORMATION ABOUT PRADAXA
PRADAXA can cause bleeding which can be serious and sometimes lead to death. Don’t take PRADAXA if you currently have abnormal bleeding or if you have ever had an allergic reaction to it.
Your risk of bleeding with PRADAXA may be higher if you:
- • are 75 years old or older
- • have kidney problems
- • have stomach or intestine bleeding that is recent or keeps coming back or you have a stomach ulcer
- • take other medicines that increase your risk of bleeding, like aspirin products, non-steroidal anti-inflammatory drugs (NSAIDs) and blood thinners
- • have kidney problems and take dronedarone (Multaq®) or ketoconazole tablets (Nizoral®)
Call your doctor or seek immediate medical care if you have any of the following signs or symptoms of bleeding:
- • any unexpected, severe, or uncontrollable bleeding; or bleeding that lasts a long time
- • unusual or unexpected bruising
- • coughing up or vomiting blood; or vomit that looks like coffee grounds
- • pink or brown urine; red or black stools (looks like tar)
- • unexpected pain, swelling, or joint pain
- • headaches and feeling dizzy or weak
It is important to tell your doctor about all medicines, vitamins and supplements you take. Some of your other medicines may affect the way PRADAXA works.
Take PRADAXA exactly as prescribed by your doctor. Don’t stop taking PRADAXA without talking to your doctor as your risk of stroke may increase.
Tell your doctor if you are planning to have any surgery, or medical or dental procedure, because you may have to stop taking PRADAXA for a short time.
PRADAXA can cause indigestion, stomach upset or burning, and stomach pain.
WHAT IS PRADAXA?
PRADAXA is a prescription blood-thinning medicine used to reduce the risk of stroke and blood clots in people with atrial fibrillation not caused by a heart valve problem. With atrial fibrillation, part of the heart does not beat the way it should. This can cause blood clots to form, increasing your risk of a stroke. PRADAXA lowers the chance of blood clots forming in your body.
Click here for full Prescribing Information including Medication Guide.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
The health information contained in this Website is provided for educational purposes only and is not intended to replace discussions with a healthcare professional. All decisions regarding patient care must be made with a healthcare professional, considering the unique characteristics of the patient.
Pradaxa® is a registered trademark of Boehringer Ingelheim Pharma GmbH & Co. KG and used under license.
The other brands listed above are trademarks of their respective owners, and are not trademarks of Boehringer Ingelheim Pharmaceuticals, Inc.
The owners of these brands are not affiliated with and do not endorse Boehringer Ingelheim Pharmaceuticals, Inc., or its products.
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